Table 2:

Total and regional WMH distribution by study group

	BIMA (n = 70)			NORMAL (n = 75)			Odds Ratio (95% CI)a	P Valuea
	No. (%) With ≥1 WMH	Mean WMH Count (SD)	Median WMH Count (Range)	No. (%) With ≥1 WMH	Mean WMH Count (SD)	Median WMH Count (Range)
Total WMH	57 (81.4)	8.6 (17.9)	3 (0–108)	45 (60.0)	8.5 (18.0)	1 (0–83)	3.49 (1.58–7.72)	.002b
Regional WMH
Frontal	52 (74.3)	6.3 (13.0)	2 (0–69)	44 (58.7)	6.0 (13.3)	1 (0–74)	2.43 (1.16–5.08)	.02b
Parietal	22 (31.4)	1.2 (3.9)	0 (0–29)	21 (28.0)	1.6 (4.5)	0 (0–29)	1.51 (0.70–3.28)	.30
Temporal	16 (22.9)	0.7 (1.9)	0 (0–10)	15 (20.0)	0.5 (1.2)	0 (0–6)	1.46 (0.62–3.45)	.39
Occipital	2 (2.9)	0.0 (0.2)	0 (0–1)	8 (10.7)	0.2 (0.5)	0 (0–2)	0.33 (0.06–1.77)	.20
Cerebellum	1 (1.4)	0.0 (0.1)	0 (0–1)	0 (0.0)	0.0 (0.0)	0 (0–0)	NA	NA
Corpus callosum genu	2 (2.9)	0.1 (0.4)	0 (0–3)	2 (2.7)	0.1 (0.3)	0 (0–2)	0.93 (0.12–6.93)	.94
Corpus callosum body	8 (11.4)	0.1 (0.4)	0 (0–2)	5 (6.7)	0.1 (0.5)	0 (0–3)	2.12 (0.6–7.51)	.25
Corpus callosum splenium	2 (2.9)	0.0 (0.2)	0 (0–1)	1 (1.3)	0.0 (0.1)	0 (0–1)	8.39 (0.29–242.91)	.22
Midbrain	1 (1.4)	0.0 (0.1)	0 (0–1)	0 (0.0)	0.0 (0.0)	0 (0–0)	NA	NA
Pons	0 (0.0)	0.0 (0.0)	0 (0–0)	1 (1.3)	0.0 (0.2)	0 (0–2)	NA	NA
Medulla	0 (0.0)	0.0 (0.0)	0 (0–0)	0 (0.0)	0.0 (0.0)	0 (0–0)	NA	NA

Note:—NA indicates not applicable.

^aResults obtained from logistic regression models of the probability of ≥1 WMH adjusted for age.

^bP < 0.05.