Skip to main content
. 2020 Jan;41(1):10–20. doi: 10.3174/ajnr.A6358

Fig 8.

Fig 8.

DSC perfusion in pseudoprogression and progressive disease. A, Axial contrast-enhanced T1-weighted and the corresponding rCBV map images show an enhancing lesion that developed after radiation therapy and temozolomide in a 46-year-old patient with multicentric GBM. The DSC perfusion of the enhancing lesion in the surgical bed (white ROI) shows decreased rCBV (0.5) in comparison with normal contralateral white matter (green ROI), which is consistent with predominance of radiation injury within the lesion (pseudoprogression). B, Axial contrast-enhanced T1-weighted and corresponding rCBV map images in a 60-year-old patient with a previously resected GBM show an enhancing lesion (white ROI) close to the margin of the radiation field. The DSC perfusion of the enhancing lesion in the surgical bed shows increased rCBV (2.8) in comparison with normal contralateral white matter (green ROI), indicating predominance of malignant cells within the lesion (progressive disease).