Fig 4.

Coronal T2-weighted images from patient 15 at 3 days (A) and again at 3 years (B) of age demonstrate the expected evolution of the signal intensity of the heterotopias—hypointense relative to surrounding unmyelinated white matter (white arrows, A), becoming hyperintense relative to surrounding myelinated white matter (white arrows, B). Coronal T1-weighted images from patient 7 at 3 days of age (C) and patient 17 at 13 months of age (D) demonstrate similar isointensity of the heterotopias (white arrows, C and D) to gray matter.