Recall-precision plot for the prediction of ligand-binding pockets by pockets and cave pockets. The 1,784 representative chains were used. The green and red lines correspond to pockets and cave pockets, respectively. The labels “I”, “II”, “III” and “A” correspond to the results using the largest cluster, the two largest clusters, the three largest clusters, and all pocket clusters. The lines labeled “P(3 Å)”, “P(4 Å)”, “P(5 Å)”, “P(6 Å)”, and “P(8 Å)” correspond to the results of pockets with Rlarge=3, 4, 5, 6 and 8 Å, respectively. Similarly, the lines labeled “CP(3 Å)”, “CP(4 Å)”, “CP(5 Å)”, “CP(6 Å)”, and “CP(8 Å)” correspond to the results of cave pockets with Rlarge=3, 4, 5, 6 and 8 Å, respectively.