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. 2019 Jun 19;24(12):1593–1600. doi: 10.1634/theoncologist.2019-0133

Table 2. Risk differences for CR rates in each study period.

image

Overall phase, days 1–5 after chemotherapy; Acute phase, 0–24 hours after chemotherapy; Delayed phase, days 2–5 after chemotherapy.

a

d1 arm: palonosetron plus 1‐day dexamethasone.

b

d3 arm: palonosetron plus 3‐day dexamethasone.

c

One‐day minus 3‐day regimen with 95% CI obtained using individual patient meta‐analysis for the overall study cohort.

d

Overall combined (pooled) result with fixed‐effect model.

e

Noninferiority hypothesis was demonstrated as the lower boundary of the 95% CI of the risk difference greater than the preset threshold (−8%).

Abbreviations: CI, confidence interval; CR, complete response; RD, risk difference.