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. 2019 Jul 25;24(12):1584–1592. doi: 10.1634/theoncologist.2019-0223

Figure 2.

image

Representative histological (A) and magnetic resonance imaging (MRI) (B) features of subgroups. (A): H&E staining shows large astroblastic pseudorosettes in all cases (upper panel). Unlike HGG and HGNET‐MN1, PXA‐like astroblastoma (ABM) demonstrate an intense cytoplasmic and pericellular expression of CD34 (lower panel). (B): Representative MRI features of subgroups. Axial post‐contrast T1‐weighted magnetic resonance images demonstrate a solid component in all cases (upper panel). Unlike the other subgroups, HGG‐like ABM show moderate‐to‐extensive perifocal edema on FLAIR sequences (lower panel).

Abbreviations: FLAIR, T2‐weighted fluid‐attenuated inversion recovery; H&E, hematoxylin and eosin; HGG, high‐grade glioma; HGNET, high grade neuroepithelial tumor; MN1, meningioma 1; PXA, pleomorphic xanthoastrocytoma; T1w, T1‐weighted.