Table 1. Study and patient characteristics.
Study | Publication type | Study design | Number of patients | Age (years) | Male/female | Prague C&M criteria | Prior treatment (n) | Baseline histopathology | Number of ablation sessions | Cryotherapy dosimetry | |||||
C | M | RFA | EMR | ND/ID | LGD | HGD | IMC | ||||||||
Scholvinck 2015 13 | Full text | MC prospective | 39 | 66 (median) | 35/4 | 2 (median) | 5 (median) | 0 | 12 | 10 | 9 | 9 | 11 | 1 | 6 s (n = 10), 8 s (n = 28), 10 s (n = 18) |
Wang 2015 14 | Abstract | SC retrospective | 5 | 65 (median) | NR | NR | NR | NR | NR | – | – | 5 | – | 1 | 10 s |
Sitaraman 2016 15 | Abstract | SC retrospective | 17 | NR | NR | NR | NR | NR | NR | – | 2 | 12 | 3 | 1 | 10 s |
Kunzli 2017 16 | Full text | SC prospective | 30 | 66 (median) | 26/4 | 0 (median) | 0 (median) | 23 | 15 | – | 14 | 7 | 9 | 1 | 10 s |
Van Munster 2018 17 | Full text | SC retrospective | 20 | 66 (median) | 17/3 | 0 (mean) | 2 (mean) | 8 | 10 | – | 9 | 11 | – | 1 | 10 s |
Canto 2018 9 | Full text | SC prospective | 41 | 65.6 (mean) | 19/22 | 1.7 (mean) | 3.9 (mean) | 19 | 14 | – | 13 | 23 | 5 | 3 (median) | 10 s |
Canto 2019 18 | Abstract | MC prospective | 120 | 64.7 (mean) | 101/19 | 1 (mean) | 3 (mean) | 0 | 54 | – | 28 | 64 | 23 | 2 (median) | 10 s |
C, circumferential extent of disease; M, maximum extent of disease; RFA, radiofrequency ablation; EMR, endoscopic mucosal resection; HGD, high-grade dysplasia; ID, infectious disease; IMC, imaging mass cytometry; LGD, low-grade dysplasia; MC, multicenter; ND no evidence of disease; NR, no response; SC, single-center