Table 3. Characteristics of patients with adverse events after fiducial placement.

	Age/Sex	Tumor	Type	Concurrent ERCP or FNA or CPN	Bile duct stent	No. of fiducials placed	Needle	Antibiotic	Chemotherapy	CyberKnife Radiation	Adverse events
1	62/M	Pancreatic Ca	Solid	ERCP	FCSEMS	4	19 g	PO Ciprofloxacin	Gemcitabine	Yes	Pain requiring hospitalization
2	65/M	Pancreatic Ca	Solid	ERCP	FCSEMS	4	19 g	IV Ciprofloxacin + PO Augmentin	–	No	Transaminitis, Major bleeding requiring transfusion
3	60/F	CholangioCa	Solid	–	FCSEMS	2	19 g	IV Ciprofloxacin	Gemcitabine, Cisplatin	Yes	Pain
4	79/F	CholangioCa	Solid	–	FCSEMS	3	19 g	–	–	Yes	Pain requiring hospitalization
5	77/F	Ampullary Ca	Solid	–	SEPS	3	19 g	–	–	Yes	Acute Cholangitis
6	69/M	CholangioCa	Solid	–	FCSEMS	3	19 g	IV Ciprofloxacin	Gemcitabine, Cisplatin	Yes	C. difficile colitis, Bacteremia
7	67/M	Pancreatic Ca	Solid	ERCP	FCSEMS	3	19 g	IV Ampicillin + IV Flagyl + PO Augmentin	–	Yes	Pancreatitis
8	63/F	Pancreatic Ca	Solid	ERCP, FNA, CPN	FCSEMS	3	19 g	IV + PO Ciprofloxacin	Gemcitabine	Yes	Pain
9	89/M	IPMN with malignant transformation	Cystic	ERCP, FNA	FCSEMS	4	19 g	IV + PO Ciprofloxacin	–	No	Septic shock
10	71/M	Pancreatic Ca	Solid	–	No stent	3	19 g	IV + PO Ciprofloxacin	Folfirinox	Yes	Minor bleeding
11	83/F	Pancreatic Ca	Mixed	CPN	FCSEMS	3	19 g	IV Ciprofloxacin	Gemcitabine	Yes	Fever, Pain
12	34/F	CholangioCa	Solid	–	UCSEMS	2	19 g	IV Ciprofloxacin	Gemcitabine, Cisplatin	Yes	Fever, Pain requiring hospitalization
13	45/F	Pancreatic NET	Solid	ERCP	UCSEMS	4	19 g	IV + PO Ciprofloxacin	–	Yes	Pancreatitis
14	78/M	Pancreatic Ca	Solid	ERCP	FCSEMS	3	19 g	IV Ciprofloxacin	–	Yes	Pain requiring hospitalization
15	59/F	Pancreatic Ca	Solid	–	No stent	4	22 g	IV Imipenem	–	Yes	Pancreatitis
16	75/F	Pancreatic Ca	Solid	–	FCSEMS	4	22 g	IV + PO Ciprofloxacin	Gemcitabine	Yes	Pain requiring hospitalization
17	68/M	CholangioCa	Solid	–	No stent	3	19 g	IV + PO Ciprofloxacin	Gemcitabine, Cisplatin	Yes	Fever, Pain requiring hospitalization
18	67/M	Pancreatic Ca	Solid	FNA	FCSEMS	3	19 g	IV + PO Ciprofloxacin	–	Yes	Pain, minor bleeding
19	66/M	Pancreatic Ca	Solid	–	No stent	4	19 g	IV Ciprofloxacin	Folfirinox	Yes	Fever requiring hospitalization
20	64/F	Pancreatic Ca	Solid	–	No stent	4	22 g	IV Ciprofloxacin + PO Augmentin	Folfirinox	Yes	Fever
21	73/M	Pancreatic Ca	Solid	–	No stent	4	22 g	IV Ciprofloxacin	–	Yes	Pain

NET, neuro-endocrine tumor; Ca, carcinoma; IPMN, intraductal papillary mucinous neoplasm; ERCP, endoscopic retrograde cholangiopancreatography; FNA, fine-needle aspiration; CPN, celiac plexus neurolysis; FCSEMS, fully-covered self-expanding metal stent; UCSEMS, uncovered self-expanding metal stent; SEPS, self-expanding plastic stent.