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Circ-ZKSCAN1 can promote tumor formation in vivo. (A,B) After inoculating A549 cells for 40 days in nude mice. (C,D) The weight and volume of tumors in the control group and the OE-circ-ZKSCAN1 group. (E) Relative circ-ZKSCAN1 expression in tumors of nude mice. (F,G) Ki-67 proliferative marker compared controls with circ-ZKSCAN1-overexpressing xenografts, as determined by IHC staining. (**P<0.01) (200×). IHC, immunohistochemistry.
