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. 2020 Jan 16;10:1562. doi: 10.3389/fphar.2019.01562

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Copyright © 2020 Espitalier, Darrouzain, Escoffre, Ternant, Piver, Bouakaz and Remerand

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Boxplots of amikacin concentration in lung and muscle tissues (N = 7–8 rabbits/condition; each rabbit was its own control). Green arrows indicate on the PKs curve the amikacin blood concentration at the time of sonoporation.