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. 2020 Jan 22;10:954. doi: 10.1038/s41598-020-57691-7

Figure 4.

Figure 4

Machine learning network models prioritize HD-relevant pathways. (A) The autophagy pathway is significantly enriched (p-value < 0.05) in the Group A compound network, a subnetwork of which is shown. The highlighted yellow region indicates those proteins that are part of the autophagy GO term. (B) The electron transport chain is significantly enriched (p-value < 0.05) in the Group B compound network, a subnetwork of which is shown. The highlighted yellow region indicates those proteins that are part of the electron transport chain GO term, part of the mitochondrial respiration pathway. See also Tables S7 and S8.