Table 3.
Correlation of different monocyte subpopulations at different time points with clinical parameters and cytokines.
| Cell population | Correlation with | pre-OP | post-OP | day 1 | day 4 | ||||
|---|---|---|---|---|---|---|---|---|---|
| r | p | r | p | r | p | r | p | ||
| Mon1 monocytes | Surgery time | 0.264 | 0.010 | 0.249 | 0.038 | ||||
| Time of CPB | 0.280 | 0.006 | |||||||
| IL-6 | 0.246 | 0.014 | |||||||
| IL-8 | −0.225 | 0.027 | |||||||
| IL-17 | −0.326 | 0.001 | |||||||
| Mon2 monocytes | Days of Hospitalization | 0.258 | 0.009 | 0.310 | 0.008 | ||||
| Time of CPB | −0.241 | 0.016 | |||||||
| Fluid balance | 0.395 | 0.001 | |||||||
| IL-4 | 0.270 | 0.008 | |||||||
| IL-6 | 0.273 | 0.006 | |||||||
| IL-17 | −0.351 | 0.001 | |||||||
| Mon3 monocytes | Days of Hospitalization | 0.280 | 0.005 | −0.280 | 0.018 | ||||
| Time of CPB | −0.234 | 0.020 | |||||||
| Fluid balance | 0.241 | 0.018 | |||||||
| IL-1β | −0.258 | 0.012 | |||||||
| IL-4 | −0.238 | 0.017 | −0.334 | 0.001 | |||||
| IL-6 | −0.326 | 0.001 | 0.248 | 0.014 | |||||
| IL-8 | −0.326 | 0.001 | 0.237 | 0.020 | |||||
| IL-12p70 | −0.245 | 0.017 | |||||||
CPB: Cardiopulmonary bypass, IL: Interleukin; Mon1, CD14++CD16− monocytes; Mon2, CD14++CD16+ monocytes; Mon3, CD14−CD16+ monocytes.
Days of Hospitalization: Overall time of stay in hospital; Fluid balance: post-OP – Fluid balance ad admission at the ICU (measured since arriving at the operation theater), day 1 and day 4: fluid balance within the last 24 hours.