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. 2019 Nov 27;2(1):fcz038. doi: 10.1093/braincomms/fcz038

Table 3.

PiB status by APOE4 and quartiles of blood amyloid-β1–42 at baseline (2000–02) and follow-up (2009) in the Pittsburgh GEMS cohort

Quartile APOE4−
APOE4+
n # PiB+ % PiB+ Age-adjusted P-value n # PiB+ % PiB+ Age-adjusted P-value
Amyloid-β1–42 baseline 1 27 16 59.3 11 10 90.9
2 30 11 36.7 7 6 85.7
3 28 14 50.0 9 8 88.9
4 33 10 30.3 0.072 4 3 75.0 0.844
Amyloid-β1–42 follow-up 1 26 13 50.0 7 7 100.0
2 25 16 64.0 6 5 83.3
3 28 9 32.1 3 1 33.3
4 23 6 26.1 0.026 7 6 85.7 0.450

Quartile cut points—amyloid-β1–42 baseline: 1Q: ≤6.36, 2Q: 6.37–9.38, 3Q: 9.39–13.86, 4Q: >13.86; amyloid-β1–42 follow-up: 1Q: ≤6.13, 2Q: 6.14–9.54, 3Q: 9.55–14.01, 4Q: >14.01. Q = quartile.