Table 5.

Logistic regression model of predictors of PiB+ (SUVR ≥1.57), log plasma amyloid-β1–42 as measured at 2000–02 and 2009 separately in the Pittsburgh GEMS cohort

Outcome = PiB+ at 2009, N = 143 (76 PiB+)			Outcome = PiB+ at 2009, N = 120 (61 PiB+)
	OR (95% CI)	P-value		OR (95% CI)	P-value
Age, per year	1.12 (0.97, 1.28)	0.123	Age, per year	1.16 (0.99, 1.36)	0.072
Years of education, per year	1.03 (0.89, 1.19)	0.680	Years of education, per year	1.02 (0.86, 1.20)	0.829
Number id="991" of blocks walked, ≤58/>58	1.28 (0.54, 3.08)	0.575	Number id="994" of blocks walked, ≤58/>58	0.93 (0.34, 2.56)	0.883
Hypertension, yes/no	1.23 (0.54, 2.82)	0.618	Hypertension, yes/no	2.08 (0.79, 5.48)	0.137
APOE4, yes/no	8.84 (2.72, 28.73)	0.000	APOE4, yes/no	7.01 (1.97, 24.96)	0.003
Ginkgo biloba intervention, yes/no	1.36 (0.64, 2.90)	0.428	Ginkgo biloba intervention, yes/no	1.28 (0.55, 2.97)	0.571
Log creatinine	1.81 (0.27, 12.19)	0.540	Log creatinine	0.92 (0.13, 6.72)	0.936
Amyloid-β1–42 at 2000			Amyloid-β1–42 at 2009
≤6.23	3.99 (1.30, 12.19)	0.015	≤5.81	2.78 (0.84, 9.17)	0.093
6.24–9.35	1.24 (0.43, 3.57)	0.693	5.82–9.34	5.99 (1.76, 20.37)	0.004
9.36–13.92	1.87 (0.65, 5.40)	0.246	9.35–14.01	1.05 (0.32, 3.43)	0.933
	N	# PiB positive		N	# PiB positive
Amyloid-β1–42 at 2000			Amyloid-β1–42 at 2009
1Q	35	25	1Q	29	16
2Q	37	17	2Q	30	23
3Q	37	21	3Q	31	10
4Q	34	13	4Q	31	12

Reference group for amyloid-β1–42 at 2000: >13.92. Reference group for amyloid-β1–42 at 2009: >14.01. Quartile cut points—amyloid-β1–42 baseline: 1Q: ≤6.36, 2Q: 6.37–9.38, 3Q: 9.39–13.86, 4Q: >13.86; amyloid-β1–42 follow-up: 1Q: ≤6.13, 2Q: 6.14–9.54, 3Q: 9.55–14.01, 4Q: >14.01. Q = quartile.