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. 2020 Jan 22;10:908. doi: 10.1038/s41598-020-57838-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Circulating miR-330-3p levels are associated with risk of primary caesarean section in women with GDM. (a), analysis of miR-330-3p expression in GDM cohort by incidence of vaginal (spontaneous) delivery (median [IQR], 1012000 [59518–1640000] copies, n = 19) and those delivered by caesarean section (median [IQR], 19278 [5677–817926] copies, n = 12). Significance determined by Mann-Whitney U Test, p = 0.012. (b), analysis of miR-330-3p expression (copies) by incidence of vaginal (spontaneous) delivery: control, (median [IQR], 23160 [8580–43841] copies, n = 24), GDM (median [IQR], 1012000 [59518–1640000] copies, n = 19) and caesarean delivery: control (median [IQR], 9957 [5216–834332] copies, n = 5), GDM (median [IQR], 19278 [5677–817926] copies, n = 12). Significance determined by Kruskal-Wallis Test adjusted by Bonferroni correction for multiple tests, p = 0.001.