Figure 5.

Distribution of z-average apparent hydrodynamic diameters, dz,app from dynamic light scattering measurements on mucin and vancomycin at differing mixing ratios (a) 0.5 mg/mL PGM + 0.125 mg/mL (blue line), +1.25 mg/mL (dark green), +12.5 mg/mL (red). The 0.5 mg/mL PGM control is shown in black. (b) 0.5 mg/mL PIM + 0.125 mg/mL (blue line), +1.25 mg/mL (dark green), +12.5 mg/mL (red). The 0.5 mg/mL PIM control is shown in black and (c) 1.0 mg/mL BSM + 0.125 mg/mL (blue line), +1.25 mg/mL (dark green), +12.5 mg/mL (red). The 1.0 mg/mL BSM control is shown in black. Because free vancomycin scatters too weakly at the concentrations in the mixtures, for the vancomycin control (purple) a higher concentration of 50 mg/mL was used.