Fig. 3.

Plasma lipoprotein profile analyzed by HPLC using a tandem TSK gel lipopropak XL (4.6 mm I.D. × 300 mm) equipped with on-line enzymatic coloring reagent system to monitor cholesterol (thick lines) and triglyceride (thin lines) (Skylight Biotech Inc, Japan)

A. Wild type mice under standard chow. B. Wild type mice fed with 0.5% probucol-containing chow. C. Abca1−/− mice under standard chow. D. Abca1−/− mice fed with 0.5% probucol chow. E. Lcat−/− mice under standard chow. F. Lcat−/− mice fed with 0.5% probucol chow. Bold solid lines indicate total cholesterol, and thin sold lines indicate triacylgrycerol. Insets to each panel show VLDL/LDL fraction and HDL fraction in expanded/magnified scale. Arrow in insets show a lipoprotein peak in HDL fraction.