Table 1. Litter size and Genotype of weaned pups of low HDL mice: Single and double asterisks indicate reduction of the litter size from Wild x Wild under standard chow as p < 0.05 and p < 0.01, respectively. Underlined Chi-squared p indicates reduction from the expected number by Mendelian genetics by p < 0.05.

	Genotype of parents	n (mating pair)	Litter size	Male %	Chi-squared p
					Gender ratio	Homozygote
						Female	Male
MF standard chow	Wild x Wild	5	10.0 ± 1.4	47.6	0.827
	Abca1+/− (f) x Abca1−/−(m)	11	6.6 ± 2.6*	37	0.059	0.078	< 0.001
	Abca1+/−x Abca1+/−	29	6.2 ± 2.3**	53.3	0.748	0.018	0.0014
	Lcat+/− (f) x Lcat−/−(m)	40	5.6 ± 2.3**	43.3	0.352	0.715	0.033
	Lcat+/−x Lcat+/−	15	7.5 ± 1.6**	46	0.249	0.920	0.024
0.2% probucol	Wild x Wild	5	8.6 ± 1.1	53.5	0.647
	Abca1+/−x Abca1+/−	27	6.3 ± 1.5*	44.2	0.122	0.010	0.022
	Lcat+/−x Lcat+/−	23	6.9 ± 2.4**	51.3	0.656	0.839	0.846