Figure 2.

Schematic of the vectors used to calculate the projected lengths. Tsr is shown in a gray tube representation. Residues 158–172 of the crystal structure of apo and serine-bound pTsr are shown in blue and red tube representations. Residues 158–172 of the simulated snapshot of pTsr bound to (R)-DHMA or (S)-DHMA are shown in a cyan tube representation. The geometric centers of residues 158–172 are shown as blue, red, and cyan spheres in the crystal structure of apo pTsr, the crystal structure of serine-bound pTsr, and the simulated snapshot of pTsr bound to (R)-DHMA or (S)-DHMA, respectively. In the zoomed-in window, vectors between the centers of mass are indicated by blue arrows. The projection of the vector λ_i-2D4U onto the baseline vector, λ_2D4U-3ATP, is indicated by a gray arrow. The resulting projected length, p_i, which is shown as a dashed green arrow. To see this figure in color, go online.