Table 3.
The Median of microRNA -215 and AFP among the Studied Groups
| Parameters | GI | GII | GIII | Test of significance Kruskal-Wallis | Post hoc test |
|---|---|---|---|---|---|
| Control | Cirrhosis | HCC | |||
| (n = 60) | (n = 75) | (n = 60) | |||
| MiRNA-215 | |||||
| Median (IQR) | 6.89 (7.33) | 2.85 (2.96) | 0.52 (1.63) | x 2 = 93.42 | p1< 0.001HS |
| p-value | p2< 0.001HS | ||||
| Range (min-max) | 1.60 - 21.30 | 0.70 - 14.65 | 0.03 - 10.95 | <0.001HS | p3< 0.001HS |
| AFP (ng/mL) | |||||
| Median (IQR) | 3.95 (2.53) | 5.50 (21.20) | 38.00 (184.76) | x 2 = 69.63 | p1= 0.001HS |
| p-value | p2< 0.001HS | ||||
| Range (min-max) | 0.80 - 10.50 | 1.01 - 110.00 | 1.80 - 3130.00 | <0.001HS | p3< 0.001HS |
a, Multiple pairwise comparisons by Post hoc test; -p1, p-value for the difference between control and cirrhosis group (GI vs. GII); -p2, p-value for the difference between control and HCC group (GI vs. GIII); p3, p-value for the difference between cirrhosis and HCC group (GII vs. GIII); IQR, Interquartile range; NS, Non significant at p-value ≥ 0.05; S, Significant at p-value < 0.05; HS, Highly significant at p-value < 0.01.