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Half Maximal Inhibitory Concentration (IC50) of Erlotinib Alone and in Combination with miRNAs in A549 Cells
| Treatment | IC50
|
|
|---|---|---|
| 24 h | 48 h | |
| Erlotinib | 21.47 ± 1.18 | 14.26 ± 1.83 |
| NC miRNA and erlotinib | 20.35 ± 1.11# | 13.17 ± 1.42# |
| miRNA-145 and erlotinib | 11.36 ± 2.13* | 7.63 ± 0.66* |
IC50 values were calculated by sigmoidal dose-response (variable slope) model using GraphPad Prism software. Results expressed as the mean±SD (n=3). *p<0.05 versus erlotinib; #p>0.05 relative to the erlotinib.
