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Inhibition of IVM‐gated currents
| GluCl receptor | LND | FIP | PTX | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 (μM) | nH | %Inhib. | n | IC50 (μM) | nH | %Inhib. | n | IC50 (μM) | nH | %Inhib. | n | |
| b1 | 3.0 ± 0.9 | 0.7 ± 0.3 | 17 ± 3 | 6 | 0.2 ± 0.1 | 0.8 ± 0.1 | 50 ± 6 | 6 | 6 ± 1 | 1.5 ± 0.3 | 20 ± 2 | 6 |
| c | 11.0 ± 0.5* | 1.0 ± 0.3 | 19 ± 6 | 6 | 0.6 ± 0.1* | 1.0 ± 0.1 | 68 ± 10* | 6 | 16 ± 5 | 1.5 ± 0.4 | 45 ± 7* | 6 |
Note. Values are means ± SEM.
P < .05, significantly different from b1 GluCl receptors for the equivalent experiment.
