Figure 8.
(a) Mean (N = 8; ±SEM) infusions and (b) percent drug‐appropriate lever responding (Lvr discrimination) for female rats trained to self‐administer oxycodone (0.15 mg·kg−1 per infusion) within 8‐hr‐extended access sessions, starting on PND112. (c) Mean (THC cohort, N = 7; PG cohort, N = 8; ±SEM) infusions during self‐administration under an FR1 schedule and (d) breakpoint values during self‐administration under a PR schedule following acute injection of THC (0.006–0.15 mg·kg−1, i.p.). & P <.05, significantly different from the first session; * P <.05, significantly different from 0.006 mg·kg−1 per infusion; # P <.05, significantly different from the 0.06 mg·kg−1 per infusion.