Table 1. Factors related to relapse in self-referred addicts to methadone maintenance therapy centers by univariate and multiple regression models.
| Variables | Relapse, n/total (%) |
Crude OR (95% CI) |
Adjusted OR (95% CI) |
|---|---|---|---|
| Sex | |||
| Male | 3091/4037 (76.6) | 1 | - |
| Female | 104/138 (75.4) | 0.92 (0.62–1.37) | - |
| Marital status | |||
| Single | 652/870(74.9) | 1 | - |
| Married | 2346/3056 (76.8) | 1.14 (0.62–1.37) | - |
| Divorced | 181/245 (73.9) | 0.94 (0.62–1.37) | - |
| Education, years | |||
| Illiterate | 167/206 (81.1) | 1 | - |
| ≤ 5 | 635/759 (83.7) | 1.19 (0.80–1.78) | - |
| 6–9 | 937/1184 (79.1) | 0.88 (0.60–1.28) | - |
| 10–12 | 1149/1559 (73.7) | 0.65 (0.45–0.94) | - |
| ≥ 13 | 310/463 (66.9) | 0.47 (0.31–0.71) | - |
| Age at first drug use, years | |||
| < 15 | 222/311 (71.4) | 1 | 1 |
| 15–19 | 1090/1467 (74.3) | 1.24 (0.93–1.65) | 1.13 (0.85–1.51) |
| 20–24 | 738/951 (77.6) | 1.65 (1.23–2.24) | 1.38 (1.01–1.87) |
| 25–29 | 542/670 (80.9) | 1.79 (1.30–2.46) | 1.76 (1.27–2.45) |
| 30–39 | 397/526 (75.5) | 1.41 (1.01–1.97) | 1.31 (0.94–1.82) |
| ≥ 40 | 211/250 (84.4) | 2.45 (1.52–3.90) | 2.32 (1.49–3.59) |
| Total budget buying substance per day, US$ | |||
| < 2 | 962/1337 (72.0) | 1 | 1 |
| 2–4.9 | 571/812 (70.3) | 0.92 (0.76–1.11) | 0.92 (0.75–1.12) |
| 5–9.9 | 361/465 (77.6) | 1.35 (1.05–1.73) | 1.38 (1.06–1.79) |
| 10–14.9 | 565/699 (80.8) | 1.64 (1.31–2.05) | 1.63 (1.30–2.07) |
| ≥ 15 | 741/862 (86.0) | 2.38 (190–2.99) | 1.41 (1.91–3.07) |
| Frequency of methadone therapy in MMT centers | |||
| Each day | 1420/1988 (71.4) | 1 | - |
| Every other day | 501/590 (84.9) | 2.25 (1.76–2.88) | - |
| Once a week | 1279/1597(80.1) | 1.68 (1.37–1.88) | - |
| History for quitting without treatment | |||
| No | 261/656 (39.8) | 1 | 1 |
| Yes | 2939/3300 (89.1) | 3.27 (2.43–4.40) | 2.14 (1.69–2.71) |
| Frequency of substance use before abstinence | |||
| Every day | 1014/1293 (78.4) | 1 | 1 |
| Every other day | 299/342 (87.4) | 1.91 (1.35–2.70) | 1.90 (1.30–2.78) |
| Once a week | 1887/2540 (74.2) | 0.79 (0.67–0.93) | 0.76 (0.64–0.91) |
| Types of substance | |||
| More than one drugs | 309/362 (85.4) | 1 | - |
| Hallucinogen | 329/450 (73.1) | 0.46 (0.32–0.66) | - |
| Stimulant drugs | 255/331 (77.0) | 0.57 (0.39–0.84) | - |
| Opium related drugs | 2090/2731 (76.5) | 0.55 (0.41–0.75) | - |
| Substance use disorder | |||
| No | 230/347 (66.3) | 1 | - |
| Yes | 2807/3648 (76.9) | 1.69 (1.34–2.14) | - |
OR: odds ratio; CI: confidence interval.