Table 1.
Effect of CM on hematological parameters.
| Female rats | |||
|---|---|---|---|
| Parameters | Control | CM 500 mg/Kg | CM 1000 mg/Kg |
| WBC (103 cells/μL) | 13.93 ± 3.20 | 10.23 ± 1.03 | 13.96 ± 3.27 |
| RBC (106 cells/μL) | 7.14 ± 0.23 | 6.56 ± 0.35 | 6.61 ± 0.12 |
| HGB (g/dL) | 15.06 ± 0.49 | 12.8 ± 0.35 | 12.6 ± 0.47 |
| HCT (%) | 44.5 ± 1.98 | 41.66 ± 0.81 | 37.93 ± 1.37 |
| MCV (fL) | 62.33 ± 1.98 | 63.96 ± 4.75 | 57.33 ± 1.27 |
| MCH (pg) | 21.13 ± 0.75 | 19.43 ± 0.51 | 19.03 ± 0.48 |
| MCHC (g/dL) | 33.9 ± 0.66 | 30.46 ± 1.73 | 33.23 ± 0.06 |
| PLT (103 cells/μL) | 814.66 ± 31.85 | 877 ± 97.07 | 1164.66 ± 175.23*** |
| RDW-CV (fL) | 31.76 ± 1.30 | 42.9 ± 10.58 | 33.4 ± 2.23 |
| PDW (fL) | 12.26 ± 0.43 | 17.7 ± 3.85 | 15.86 ± 2.22 |
| MPV (fL) | 10.26 ± 0.08 | 10.26 ± 0.60 | 10.53 ± 0.26 |
| P-LCR (%) | 8.36 ± 0.06 | 8.03 ± 0.29 | 8.2 ± 0.2 |
| PNN (%) | 13.83 ± 0.58 | 12.73 ± 1.66 | 13.53 ± 1.23 |
| PNE (%) | 17.66 ± 7.17 | 25.66 ± 6.17 | 32 ± 10.44 |
| PNB (%) | 3.66 ± 1.76 | 3.66 ± 1.45 | 2 ± 1.52 |
| LYM (%) | 0.33 ± 0.33 | 0.6 ± 0.66 | 1 ± 0.57 |
| MON (%) | 77 ± 8.50 | 67 ± 6 | 61 ± 8.71 |
| Male rats | |||
|---|---|---|---|
| Parameters | Control | CM 500 mg/Kg | CM 1000 mg/Kg |
| WBC (103 cells/μL) | 13.13 ± 1.61 | 10.76 ± 0.31 | 12.3 ± 2.67 |
| RBC (106 cells/μL) | 8.39 ± 0.23 | 8.05 ± 0.40 | 8.59 ± 0.13 |
| HGB (g/dL) | 14.93 ± 0.32 | 14.16 ± 0.24 | 15.03 ± 0.27 |
| HCT (%) | 47.73 ± 0.77 | 45.6 ± 0.65 | 48.4 ± 0.75 |
| MCV (fL) | 56.96 ± 1.15 | 56.8 ± 2.00 | 56.2 ± 0.91 |
| MCH (pg) | 17.8 ± 0.30 | 17.66 ± 0.75 | 17.5 ± 0.40 |
| MCHC (g/dL) | 31.3 ± 0.17 | 31.06 ± 0.38 | 31.03 ± 0.18 |
| PLT (103 cells/μL) | 754.33 ± 75.64 | 794 ± 45.40 | 801.66 ± 89.27 |
| RDW-CV (fL) | 34.16 ± 0.66 | 36.53 ± 0.23 | 35.23 ± 0.98 |
| PDW (fL) | 16.86 ± 0.77 | 18.46 ± 1.58 | 18.3 ± 0.17 |
| MPV (fL) | 11.9 ± 0.15 | 10.56 ± 0.23 | 11.2 ± 0.62 |
| P-LCR (%) | 8.86 ± 0.18 | 8.36 ± 0.14 | 8.46 ± 0.21 |
| PNN (%) | 18.43 ± 1.41 | 14.03 ± 0.95 | 15.23 ± 1.81 |
| PNE (%) | 36.66 ± 4.05 | 24 ± 3.51 | 18.66 ± 0.88 |
| PNB (%) | 3.66 ± 0.88 | 0.33 ± 0.33 | 3.66 ± 0.88 |
| LYM (%) | 0.66 ± 0.33 | 1 ± 0.57 | 2 ± 1.15 |
| MON (%) | 58 ± 2.88 | 72 ± 3.60 | 69.66 ± 1.45 |
Effect of CM extract on serum biochemical parameters in subchronic toxicity in rats. Data are expressed as Mean ± SEM (n = 5). One-way ANOVA followed by Tukey's multiple comparisons test. Compared to control group: *** P < 0.001.