Table 2.
Differences in stress-induced functional connectivity changes between controls and patients for the whole brain analyses.
| Brain area | Hemisphere | Peak voxels (MNI coordinates) | Cluster size (# of voxels) | Significance level (p = ..) | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Increased FC of the SN in the ND group (stress – neutral) compared to the control group (stress – neutral) with: | ||||||
| Lateral Occipital Cortex, inferior division | Ri | 40 | −76 | 0 | 8 | 0.045* |
| Increased FC of the DMN in the SR group (stress – neutral) compared to the control group (stress – neutral) with: | ||||||
| PCC/Precuneus | Ri | 10 | −54 | 32 | 47 | 0.018* |
| Increased FC of the Ri FPN in the control group (stress – neutral) compared to the combined patient group (stress – neutral) with: | ||||||
| Precuneus | Ri | 12 | −60 | 48 | 5 | 0.046* |
| Increased FC of the Le FPN in the control group (stress – neutral) compared to the CM group (stress – neutral) with: | ||||||
| Middle Frontal Gyrus | Ri | 56 | 14 | 40 | 14 | 0.033* |
Abbreviations: CM: comorbidity, DMN: default mode network, FC: functional connectivity, FPN: frontoparietal network, Le: left, MNI: Montreal Neurological Institute, ND: neurodevelopmental, PCC: posterior cingulate cortex, Ri: right, SN: salience network, SR: stress-related.
⁎
p < 0.05.