Figure 3.

Impacts of parental HFD on the body weight and liver weight of offspring. (A) A schematic study design. After being fed with either a LFD or HFD for 8 weeks at an age of 4–5 weeks, mice were mated. The offspring were sacrificed at different ages after birth (n = 3–6 per group). Body weight (B) and liver weight (C) of offspring were measured. Data are depicted as mean ± SD. Each dot represents a value from one mouse. Statistical significance between two groups was determined by an unpaired Student's t-test. *P < 0.05, **P < 0.01, ***P < 0.001, HFD versus the age-matched LFD groups.