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. 2019 Nov 28;10(1):171–185. doi: 10.1016/j.apsb.2019.10.009

Figure 6.

Figure 6

Impacts of HFD-feeding durations of parental mice on the body weight and liver weight of offspring. (A) A schematic study design. After being fed with either a LFD or HFD for 4 or 18 weeks at an age of 4–5 weeks, mice were mated. The offspring were sacrificed at different ages after birth (n = 3–6 per group). Body weight and liver weight of offspring were measured. (B) Body weight and liver weight of male and female offspring (postnatal days 15, 20, 30, or 60) derived from parental mice fed with a LFD or HFD for 4 weeks. (C) Body weight and liver weight of male offspring (postnatal day 60) derived from parental mice fed with a LFD or HFD for 18 weeks. Data are depicted as mean ± SD. Each dot represents a value from one mouse. Statistical significance between two groups was determined by an unpaired Student's t-test. **P < 0.01, ***P < 0.001, HFD versus the age-matched LFD groups.