Table 2.
Clinical characteristics for univariate analysis of PNH patients
| Variable | N (%) | 10‐year OS | P |
|---|---|---|---|
| Number of patients | 65 | 70.77% | |
| Age | |||
| ≧60 | 9 (13.85) | 57.89% | .026 |
| <60 | 56 (86.15) | 71.43% | |
| Sex | |||
| Male | 37 (56.92) | 72.84% | .653 |
| Female | 28 (43.08) | 70.69% | |
| LDH increased times | |||
| <5 | 34 (52.31) | 71.75% | .019 |
| ≧5 | 31 (47.69) | 41.12% | |
| CD59− neutrophils | |||
| ≧50% | 38 (58.46) | 55.55% | .148 |
| <50% | 27 (41.54) | 52.45% | |
| Combined thrombosis | |||
| Yes | 11 (16.92) | 53 mo | .0001 |
| No | 54 (83.08) | 88.92% | |
| Combined BMF | |||
| Yes | 17 (26.15) | 50.45% | .003 |
| No | 48 (73.85) | 71.75% | |
| Renal function | |||
| Normal | 50 (76.92) | 72.09% | .0001 |
| CKD1‐2 | 12 (18.46) | 70.79% | |
| CKD3‐5 | 3 (4.62) | 69 mo | |
Abbreviations: BMF, bone marrow failure; CKD, chronic kidney disease; LDH, lactate dehydrogenase; OS, overall survival.