Fig. 2.

Graphical representation of the experimental logarithmic solubility (mole/mole) of the APIs in the DESs, water, and conventional solvents. The colours green and red indicate high and low solubility, respectively. The solubility of aprepitant and probucol was below the limit of quantification in water and the missing data is indicated by a cross. The circles indicate API-DES combinations that outperform conventional pharmaceutical solvents in a w/w solubility. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)