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. 2020 Jan 22;18(1):1559325819901242. doi: 10.1177/1559325819901242

Figure 6.

Figure 6.

Effects of 3-aminobenzamide (3-AB) on ultrastructure of microvessels’ tight junction (TJ) in penumbra and core in ischemic tissue at I 1.5 h/R 4.5 h and I 1.5 h/R 22.5 h after middle cerebral artery occlusion (MCAO) in rats. Vehicle or 3-AB was injected intraperitoneally 1 hour after ischemia. Images in penumbra are shown in A-E. A, Sham-operated group; B, vehicle-treated group at I 1.5 h/R 4.5 h; C, 3-AB-treated group at I 1.5 h/R 4.5 h; D, vehicle-treated group at I 1.5 h/R 22.5 h; E, 3-AB-treated group at I 1.5 h/R 22.5 h. Images in core are shown in F-J. F, Sham-operated group; G, vehicle-treated group at I 1.5 h/R 4.5 h; H, 3-AB-treated group at I 1.5 h/R 4.5 h; I, vehicle-treated group at I 1.5 h/R 22.5 h; J, 3-AB-treated group at I 1.5 h/R 22.5 h (original magnification 7500×). Red and blue notes indicate the TJ and basement membrane (BM) of the microvessels, respectively.