Table 1.

Univariate Cox proportional hazard model of overall survival and margins between contrast enriching tumor volumes and beam collimation settings

Variable (Univariate analyses)	Hazard ratio (95% Confidence interval)	P-value	P-value adjusted (Bonferroni-Holm)
Margin H-axis mean over time (d7, d10, d14, d17) [mm]	0.53 (0.35–0.81)	0.0034	0.0136
Margin H-axis d7 [mm]	0.67 (0.50–0.90)	0.0088	0.0264
Margin L-axis mean over time (d7, d10, d14, d17) [mm]	0.50 (0.26–0.93)	0.0284	0.0568
Margin L-axis d7 [mm]	0.65 (0.32–1.32)	0.2318	0.2318

Margin sizes between contrast enriching tumor volumes and beam collimation settings in H- and L-axis [mm] as means over time (d7, d10, d14, d17) or as single values of d7 and overall survival times [d] were subjected to univariate Cox proportional hazard model analyses and post-hoc Bonferroni-Holm correction