Table 3.
Primary and secondary outcomes after PSM
| Outcome | Control (N = 94) | iNO treatment (N = 40) | p-value |
|---|---|---|---|
| Primary outcome | |||
| Mechanical ventilation time (hours) | 69.0(47.8, 110.3) | 39.0(31.2, 47.8) | < 0.001 |
| ICU stay (hours) | 179.5(114.0, 258.0) | 122.0(80.8, 155.0) | < 0.001 |
| Secondary outcome | |||
| Inpatient deaths N (%) | 7 (7.4) | 1 (2.5) | 0.479 |
| In-hospital stay (days) | 20.5(15.8, 28.5) | 22.8(19.1, 27.5) | 0.131 |
| Postoperative drainage (24 h) | 470(325, 750) | 495(260, 667) | 0.216 |
| Peak CRP (mg/L) | 7.1(2.4, 85.7) | 8.0(2.6, 37.9) | 0.676 |
| Complication. | |||
| Cardiac arrest | 2 (2.1) | 0 (0.0) | 0.880 |
| Re-intubation | 7 (7.4) | 2 (5.0) | 0.888 |
| Pneumonia | 23 (24.5) | 5 (12.5) | 0.110 |
| Hepatic insufficiency | 20 (21.3) | 4 (10.0) | 0.119 |
| AKI | 55 (58.5) | 19 (47.5) | 0.241 |
| CRRT | 7 (7.4) | 2 (5.0) | 0.605 |
| Paraplegia | 1 (1.1) | 0 (0.0) | 0.513 |
| Sepsis | 6 (6.4) | 4 (10.0) | 0.466 |
| Re-exploration for bleeding | 2 (2.1) | 2(5.0) | 0.734 |
| thrombocytopenia | 28 (29.8) | 13 (32.5) | 0.755 |
PSM Propensity score-matching, iNO Inhaled nitric oxide, ICU Intensive care unit, CRP C-reactive protein, AKI Acute kidney injury, CRRT Continuous renal replacement therapy