Table 1.

Summary of concordance between GeT‐RM and PharmCAT results

Gene	Number of samplesa	Number of concordant samplesb	% Concordance
CYP2C19 c	59	59	100
CYP2C9	59	59	100
CYP3A5	59	59	100
CYP4F2	45	36	80.0
DPYD d	59	56	94.9
IFNL3 e	59	59	100
SLCO1B1 d	59	5	8.5
TPMT	59	58	98.3
UGT1A1 d	45	24	53.3
VKORC1	59	59	100

CYP, cytochrome P450; GeT‐RM, Genetic Testing Reference Materials Coordination Program.

^aNumber of GeT‐RM characterized Coriell samples with available 1000 Genome VCF files (1000 Genomes Phase 3 data release). ^bNumber of samples with agreement between GeT‐RM consensus genotypes and PharmCAT‐derived genotypes using 1000 Genomes VCF files. ^c CYP2C19*1/*4 is considered concordant to CYP2C19*1/*4A based on presence of rs28399504; c.1A>G. ^dDetails of how concordance was calculated are described in the Supplementary Material . ^eGeT‐RM IFNL3 genotypes retrieved from the non consensus table (only one testing company provided IFNL3 genotypes).