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. 2019 Sep 6;34(1):e23028. doi: 10.1002/jcla.23028

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© 2019 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals, Inc.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Expression of SMAD3 and miR‐145 in human aortic samples in the non‐AD control and AD groups, respectively. A and B, Immunoblot demonstrated the amounts of the SMAD3 protein in human aortic samples (n = 4 per group). The AD group showed significantly increased SMAD3 amounts (P < .01). C, qPCR demonstrated the expression of SMAD3 mRNA in human aortic samples (n = 6 and 4 for the AD and non‐AD control groups, respectively). The expression of SMAD3 mRNA significantly increased in the AD group (P < .01). D, qPCR was employed to assess miR‐145 amounts in human aortic samples (n = 6 and 4 for the AD and non‐AD control groups, respectively). miR‐145 amounts were markedly downregulated in the AD group (P < .05)