Table 1.
Patient demographic and clinical characteristics.
| Not on Anticoagulants n = 189 | Not Reversed n = 84 | Reversed n = 186 | p | |
|---|---|---|---|---|
| Age Median (IQR) | 82 (76, 88) | 83.5 (75.5, 88) | 83.5 (78, 88) | 0.39 |
| Sex % Female (n) | 68% (128) | 71% (60) | 62% (116) | 0.29 |
| Pre-ambulatory Status | ||||
| Walks without an assistive device | 68% (128) | 62% (50) | 55% (100) | 0.01a |
| Walks with an assistive device | 27% (50) | 38% (31) | 41% (75) | |
| Cannot walk | 5% (9) | 0 | 3% (6) | |
| Prior Hip Fracture | 9% (16) | 8% (7) | 11% (21) | 0.54 |
| Pre-injury Medications | ||||
| Cholinesterase Inhibitors | 12% (22) | 12% (10) | 10% (19) | 0.88 |
| Analgesic | 15% (28) | 26% (22) | 26% (48) | 0.02b |
| Narcotic | 15% (29) | 31% (26) | 27% (51) | 0.004c |
| Anti-arrhythmia | 1% (2) | 29% (24) | 30% (56) | <0.001d |
| Beta Blocker | 15% (29) | 35% (33) | 28% (54) | <0.001e |
| Calcium Channel Blockers | 22% (42) | 24% (20) | 24% (44) | 0.93 |
| Vitamin D | 21% (40) | 17% (14) | 26% (48) | 0.22 |
| Iron | 6% (11) | 8% (7) | 9% (16) | 0.55 |
| Potassium | 11% (20) | 18% (15) | 19% (36) | 0.05 |
| Statin | 32% (61) | 36% (30) | 50% (93) | 0.001f |
| Medication Count Median (IQR) | 5 (2, 8) | 6 (4, 9) | 7 (5, 10) | <0.001g |
| Comorbidities | ||||
| Diabetes Mellitus | 18% (34) | 14% (12) | 25% (46) | 0.09 |
| Hypertension | 63% (119) | 62% (52) | 65% (120) | 0.91 |
| Congestive Heart Failure | 8% (16) | 14% (12) | 23% (42) | <0.001h |
| Dementia | 24% (46) | 14% (12) | 18% (34) | 0.12 |
| COPD | 15% (29) | 10% (8) | 15% (28) | 0.40 |
| Smoker | 8% (16) | 6% (5) | 6% (11) | 0.58 |
| Cerebrovascular Accident | 5% (10) | 8% (7) | 11% (21) | 0.11 |
| Anemia | 0 | 1% (1) | 1% (1) | 0.18 |
| Cancer | 1% (2) | 0 | 2% (4) | 0.50 |
| Admission Vital Signs | ||||
| SBP Median (IQR) | 144 (129, 166) | 148.5 (129, 168.5) | 144 (127, 161) | 0.53 |
| DBP Median (IQR) | 75 (67, 86) | 81 (70, 94) | 77 (67.5, 89) | 0.41 |
| RR Median (IQR) | 18 (16, 18.5) | 16 (16, 18) | 18 (16, 18) | 0.58 |
| HR Median (IQR) | 79 (70, 90) | 76 (68, 87.5) | 80 (70, 89.5) | 0.33 |
| O2 Median (IQR) | 95 (93, 98) | 94.5 (92, 97) | 96 (94, 97) | 0.21 |
Bonferroni-adjusted p = 0.025, N/A = not applicable, no values collected for this patient group; therefore, p-value not calculated. a = A higher proportion of reversed patients walked with an assistive device than those not on anticoagulants, no significant difference between those not on anticoagulants and those reversed, p = 0.04, or those not reversed and reversed, p = 0.23. b = A higher proportion of patients on anticoagulants than those not on anticoagulants were taking pre-injury analgesics, no significant difference between those not reversed and reversed, p = 0.95. c = A higher proportion of patients on anticoagulants than patients not on anticoagulants were taking narcotics, no significant difference between those reversed and not reversed, p = 0.55. d = A higher proportion of patients on anticoagulants than patients not on anticoagulants were taking anti-arrhythmia medication, no significant difference between those not reversed and reversed, p = 0.80. e = A higher proportion of reversed patients were than those not on anticoagulants were taking pre-injury beta-blockers, no significant difference between those not on anticoagulants and those not reversed, p = 0.36, or those reversed and not reversed, p = 0.08. f = A higher proportion of reversed patients were taking pre-injury statins than those not on anticoagulants, no significant difference between those not on anticoagulants and those not reversed, p = 0.58, or those reversed and not reversed, p = 0.03. g = Patients on anticoagulants had a higher medication count than those not on anticoagulants, no significant difference between those reversed and not reversed, p = 0.17. h = A higher proportion of reversed patients were than those not on anticoagulants had congestive heart failure, no significant difference between those not on anticoagulants and those not reversed, p = 0.14, or between those not reversed and reversed, p = 0.11.