Table 4.
Hip fracture and procedure details.
| Not on Anticoagulants n = 189 | Not Reversed n = 84 | Reversed n = 186 | p | |
|---|---|---|---|---|
| Fracture Type | ||||
| Intertrochanteric | 50% (93) | 48% (45) | 46% (87) | 0.68 |
| Femoral Neck | 47% (87) | 49% (46) | 50% (95) | 0.84 |
| Peritrochanteric | 2% (3) | 2% (2) | 1% (1) | 0.38 |
| Subtrochanteric | 8% (15) | 6% (6) | 8% (16) | 0.83 |
| Clinical Labs | ||||
| Pre-Op Hemoglobin Mean (SD) | 11.7 (2.1) | 13.0 (2.1) | 11.2 (2.2) | <0.001a |
| Op. Hemoglobin Median (IQR) | 11.61 | 121 | 8 (7.6, 7.9) | N/A |
| Post-Op Hemoglobin Median (IQR) | 10.6 (9.2, 12.5) | 10.4 (9.9, 11.7) | 9.8 (8.9, 12.2) | 0.92 |
| Hemoglobin Drop Median (IQR) | −0.6 (−2.1, 0.1) | −1.2 (−1.8, −0.5) | −0.1, (−0.8, 0.2) | 0.43 |
| Pre-Op INR Median (IQR) | 1.1 (1.0, 1.2) | 1.4 (1.2, 2.0) | 1.6 (1.3, 1.8) | <0.001b |
| Post-Op INR Median (IQR) | 6.4 (1.1, 11.6) | 3.3 | 1.3 (1.2, 1.5) | N/A |
| ALT Median (IQR) | 21 (17, 27) | 21 (17, 28) | 22 (19, 28) | 0.52 |
| Cr Median (IQR) | 1.0 (0.8, 1.2) | 0.9 (0.7, 1.2) | 1.0 (0.8, 1.3) | 0.16 |
| Lactate Median (IQR) | 1.4 (1.1, 1.9) | 1.2 (1.0, 2.4) | 1.5 (1.2, 1.9) | 0.75 |
| K Median (IQR) | 4 (3.7, 4.2) | 4 (3.8, 4.3) | 4.1 (3.8, 4.3) | 0.12 |
| CrCl Abnormal (<60) % (n) | 90% (171) | 86% (72) | 92% (172) | 0.22 |
| Time to Surgery Median (IQR) | 20 (15, 28) | 17 (12, 23) | 33 (24, 44) | <0.001c |
| Procedures | ||||
| Bipolar Hemiarthroplasty | 4% (8) | 15% (13) | 10% (19) | 0.006d |
| Individual Screw Placement | 3% (5) | 5% (4) | 3% (5) | 0.60 |
| Total Hip Arthroplasty | 10% (19) | 14% (12) | 7% (13) | 0.16 |
| Locking Plate | 3% (5) | 2% (2) | 5% (9) | 0.42 |
| Dynamic Hip Screw Placement | 7% (14) | 2% (2) | 7% (13) | 0.26 |
| Hemiarthroplasty | 20% (37) | 6% (5) | 16% (29) | 0.02e |
| Intramedullary Fixation | 55% (104) | 55% (46) | 53% (98) | 0.89 |
| Internal Fixation | 10% (19) | 12% (10) | 22% (41) | 0.004f |
Bonferroni-adjusted p = 0.025, N = number of patients, p = p-value, pre-op = pre-operative, SD = standard deviation, op. = operative, IQR = interquartile range, post-op = post-operative, ALT = Alanine Aminotransferase, Cr = creatinine, K = potassium, CrCl = creatinine clearance. 1 = Only one patient with operative hemoglobin collected. a = Patients reversed and not on anticoagulants had a significantly lower pre-op hemoglobin than those not reversed, no significant differences observed between those reversed and not on anticoagulants, p = 0.11. b = The pre-op INR for patients on anticoagulants was significantly higher than those not on anticoagulants, no significant differences between those reversed and not reversed, p = 0.68. c = Reversed patients had a significantly longer time to surgery than those not on anticoagulants and those not reversed, no significant differences observed between those not reversed and those not on anticoagulants, p = 0.04. d = Patients on anticoagulants had significantly more bipolar hemiarthroplasties than those not on anticoagulants, no statistical difference observed for patients reversed and not reversed, p = 0.22. e = Patients not on anticoagulants had a higher proportion of hemiarthroplasties than those not reversed, no significant difference between those not on anticoagulants and those reversed, p = 0.31, or between those not reversed and reversed, p = 0.03. f = Reversed patients had significantly more internal fixation devices placed than those not on anticoagulants, no significant difference between those not reversed and not on anticoagulants, p = 0.65, or not reversed and reversed, p = 0.05.