Table 6.
Adjusted models for outcomes and complications by study arm.
| Not on Anticoagulants n = 189 | Not Reversed n = 84 | Reversed n = 186 | Model p-value | |
|---|---|---|---|---|
| Total Volume of pRBC Transfused n = 115 | ||||
| LS Mean (SE)a | 581 (58) | 511 (106) | 743 (54) | 0.008 |
| LS Mean (CI) Differencea | −161 (−317, −5) | −232 (−470, 6) | Reference | |
| p-difference | 0.04 | 0.06 | Reference | |
| Total Volume of Blood Loss n = 443 | ||||
| LS Mean (SE)b | 138 (12) | 134 (17) | 159 (12) | 0.001 |
| LS Mean (CI) Differenceb | −21 (−48, 7) | −25 (−62, 12) | Reference | |
| p-difference | 0.14 | 0.18 | Reference | |
| Hospital LOS n = 448 | ||||
| LS Mean (SE)c | 6.8 (0.4) | 6.3 (0.6) | 7.7 (0.4) | <0.001 |
| LS Mean (CI) Differencec | −0.9 (−1.6, −0.1) | −1.4 (−2.4, −0.3) | Reference | |
| p-difference | 0.02 | 0.01 | Reference | |
| ICU LOS n = 57 | ||||
| LS Mean (SE)d | 7.3 (1.8) | 6.6 (2.7) | 8.5 (1.8) | 0.005 |
| LS Mean (CI) Differenced | −1.2 (−5.2, 2.9) | −1.9 (−7.5, 3.6) | Reference | |
| p-difference | 0.56 | 0.49 | Reference | |
Bonferroni-adjusted p = 0.025, LS = least-squared mean, SE = standard error, CI = confidence internal, p-difference = p-value for the difference in LS Means, a = adjusted for enrolling facility, b = adjusted for hemiarthroplasty and enrolling facility, c = adjusted for pre-ambulatory status and enrolling facility, d = adjusted for total hip arthroplasty and enrolling facility. Variables available to adjusted models: pre-ambulatory status, pre-operative hemoglobin, pre-operative INR, enrolling facility, pre-injury potassium, pre-injury statins, preinjury analgesics, bipolar hemiarthroplasty, hemiarthroplasty, total hip arthroplasty, internal fixation, and congestive heart failure.