. 2020 Jan 11;26:e918281-1–e918281-11. doi: 10.12659/MSM.918281

Table 3.

The 365 Differentially Expressed Genes (DEGs) were identified from 4 profile datasets, including 212 upregulated genes and 153 downregulated genes in the Triple-Negative Breast Cancer (TNBC) tissues compared to normal breast tissues.

DEGs	Genes name
Upregulated	CXCR4,IRAK1,GPSM2,CCNB1,CAPS,CCNE1,FOXM1,TOR3A,EN1,TTLL4,GNB4, KIF14,MAD2L1, TTC13, KIF4A, SQLE, MCM10, TYMS, MELK, HN1, NDC80, OIP5, CCNA2, HRASLS, MMP1, STMN1, CKS2, DEPDC1, BRI3BP, IDO1, LMNB1, SPAG5, CCNB2, PRC1, LRP8, CCNE2, MCM4, WISP1, CXCL10, CKAP2L, SULF1, CDCA2, RPP25, EXO1, HPSE, KDELR2,COL11A1, HIST1H1C, HORMAD1, NEK2,TMEM206, BAIAP2L1, C1orf106, ATP6V0B, EZH2, CHEK1, KIF11, TAP1, KIFC1, MASTL, VGLL1, ARNTL2, HIST2H2AA4, RRS1, PYCR1, KCNK1, CENPA, RNFT2, CDCA7, CENPN, BUB1, TNFRSF12A, OASL, TRIP13, CDC7, UBE2S, DDIT4, LYN, IFI6, MND1, SDC1, RRM2, HNRNPAB, TOP2A, FEN1, RAD54L, PKMYT1, LRRC59, KIF18A, FAM83D, CHAF1B, PPP1R14C, HDGF, COL5A1, PRAME, CTHRC1, UHRF1, CDKN2A, RECQL4, CDKN3, CENPM, FAM64A, CENPF, RANGAP1, CDCA8, TPX2, ANP32E, KPNA2, ANLN, BIRC5, LAMP3, KLRG2, RACGAP1, EZR, CDC6, APOBEC3B, AURKA, FN1, AURKB, CTSB, FANCA, TMEM79, SPP1, IL4I1, IMPA2, USP18, DHCR7, ZWINT, GTSE1, NUF2, PTTG1, CDCA5, UBE2T, BCL2A1, RGS1, TEAD4, PPP1CA, ECT2, MMP11, MYBL1, GGH, HMOX1, PARP12, PPP1R14B, TACC3, CLEC7A, DCBLD1, CFL1, CEP55, GZMB, MFAP2, DLGAP5, RAD51AP1, TBC1D7, MKI67, TMEM123, IL32, LYZ, NMU, GAPDH, SLC39A1, KIAA0101, HSD17B6,GINS2, DONSON, E2F8, TSTA3, S100P, HMGB3, HOMER3, FLVCR1, SLC39A7, C16orf59, ADAMDEC1, TMEM45A, IDH2, CXCL11, STK38L, OAS3, ZIC1, BLM, KIF2C, CCNYL1, TUBB3, PBK, S100A11, PHF5A, TK1, SHCBP1, ASPM, INHBA, ATAD2, BRIP1, IFI30, GJB2, ICAM1, CXCL9, SPC25, KIF15, HJURP, ATP6V1C2, RSAD2, RAD51, HMMR, ART3, KIF20A, SOX11, P4HB, CHAC2, TTK, NCAPG, NUSAP1
Downregulated	KLHL13, IGF1, PPP1R14A, NAP1L2, FGFR1, NOSTRIN,NFIA, ARL4A, CNN1, MAOA, BCL2, MYBPC1, IRS1, BDH2, OXTR, TFAP2B, ZBTB20, HLF, DCX, LAMB3, PLSCR4, VIT, CMYA5, SEMA3G, PDGFD, FAM3B, NTN4, KIT, SCN4B, C1orf115, SH3BGRL2, HOXA5, RUNX1T1, WIF1, FMOD, SETBP1, MME, SCGB1D2, GPD1L, FOXO1, PDK4, CA12, BEND5, RERGL, CTTNBP2, GRAMD1C, NR3C2, SASH1,NTRK2, FTO, OLFM4, TCEAL7, PLAT, NBEA, ABCA6, C4orf32, PDGFA, MUCL1, APOD, CBX7, RAI2, SPATA18, LHFP, NME5, GNG11, RHOJ PGR, SRPX, NAV3, SSPN, AK5, ANKRD30A, GFRA1, CPE RSPO3, CX3CR1, ABCA5, TMTC1, CYBRD1, TFF1, SYNM,C2orf40,AMIGO2, AGR2, PTN, CXCL14, ITIH5, LGR6, AGR3, KIAA1683, DACH1, PTHLH, SLC40A1, CD36, DCLK1, TSHZ2, NR3C1, DNALI1, EDN3, EDNRB, MYH11, EGFLAM, SALL2, NRG2, RUNDC3B,GLI3,INHBB,SCGB2A1, HOXA7, DYNLRB2, PDE2A, ATP1A2, ACADSB, IGSF10, CDO1, SEPP1, SDPR, FOXA1, CXCL12,CX3CL1, COL14A1, SCGB2A2, ABAT, CAV1, TNS4, CCL28, JAM2, IRX2, HOXA4, DST, ITM2A, GPRASP1, C1orf226, FMO2, C3orf18, IL33, ME3, SCUBE2, PDZK1, CIRBP, CLDN8, PPP1R3C, STC2, THSD4, MAMDC2, TESC, ADAMTS5, AR, TFF3, SFRP1, SEMA3C, GRAMD3, NDN

DEGs

Genes name

Upregulated

CXCR4,IRAK1,GPSM2,CCNB1,CAPS,CCNE1,FOXM1,TOR3A,EN1,TTLL4,GNB4, KIF14,MAD2L1, TTC13, KIF4A, SQLE, MCM10, TYMS, MELK, HN1, NDC80, OIP5, CCNA2, HRASLS, MMP1, STMN1, CKS2, DEPDC1, BRI3BP, IDO1, LMNB1, SPAG5, CCNB2, PRC1, LRP8, CCNE2, MCM4, WISP1, CXCL10, CKAP2L, SULF1, CDCA2, RPP25, EXO1, HPSE, KDELR2,COL11A1, HIST1H1C, HORMAD1, NEK2,TMEM206, BAIAP2L1, C1orf106, ATP6V0B, EZH2, CHEK1, KIF11, TAP1, KIFC1, MASTL, VGLL1, ARNTL2, HIST2H2AA4, RRS1, PYCR1, KCNK1, CENPA, RNFT2, CDCA7, CENPN, BUB1, TNFRSF12A, OASL, TRIP13, CDC7, UBE2S, DDIT4, LYN, IFI6, MND1, SDC1, RRM2, HNRNPAB, TOP2A, FEN1, RAD54L, PKMYT1, LRRC59, KIF18A, FAM83D, CHAF1B, PPP1R14C, HDGF, COL5A1, PRAME, CTHRC1, UHRF1, CDKN2A, RECQL4, CDKN3, CENPM, FAM64A, CENPF, RANGAP1, CDCA8, TPX2, ANP32E, KPNA2, ANLN, BIRC5, LAMP3, KLRG2, RACGAP1, EZR, CDC6, APOBEC3B, AURKA, FN1, AURKB, CTSB, FANCA, TMEM79, SPP1, IL4I1, IMPA2, USP18, DHCR7, ZWINT, GTSE1, NUF2, PTTG1, CDCA5, UBE2T, BCL2A1, RGS1, TEAD4, PPP1CA, ECT2, MMP11, MYBL1, GGH, HMOX1, PARP12, PPP1R14B, TACC3, CLEC7A, DCBLD1, CFL1, CEP55, GZMB, MFAP2, DLGAP5, RAD51AP1, TBC1D7, MKI67, TMEM123, IL32, LYZ, NMU, GAPDH, SLC39A1, KIAA0101, HSD17B6,GINS2, DONSON, E2F8, TSTA3, S100P, HMGB3, HOMER3, FLVCR1, SLC39A7, C16orf59, ADAMDEC1, TMEM45A, IDH2, CXCL11, STK38L, OAS3, ZIC1, BLM, KIF2C, CCNYL1, TUBB3, PBK, S100A11, PHF5A, TK1, SHCBP1, ASPM, INHBA, ATAD2, BRIP1, IFI30, GJB2, ICAM1, CXCL9, SPC25, KIF15, HJURP, ATP6V1C2, RSAD2, RAD51, HMMR, ART3, KIF20A, SOX11, P4HB, CHAC2, TTK, NCAPG, NUSAP1

Downregulated

KLHL13, IGF1, PPP1R14A, NAP1L2, FGFR1, NOSTRIN,NFIA, ARL4A, CNN1, MAOA, BCL2, MYBPC1, IRS1, BDH2, OXTR, TFAP2B, ZBTB20, HLF, DCX, LAMB3, PLSCR4, VIT, CMYA5, SEMA3G, PDGFD, FAM3B, NTN4, KIT, SCN4B, C1orf115, SH3BGRL2, HOXA5, RUNX1T1, WIF1, FMOD, SETBP1, MME, SCGB1D2, GPD1L, FOXO1, PDK4, CA12, BEND5, RERGL, CTTNBP2, GRAMD1C, NR3C2, SASH1,NTRK2, FTO, OLFM4, TCEAL7, PLAT, NBEA, ABCA6, C4orf32, PDGFA, MUCL1, APOD, CBX7, RAI2, SPATA18, LHFP, NME5, GNG11, RHOJ PGR, SRPX, NAV3, SSPN, AK5, ANKRD30A, GFRA1, CPE RSPO3, CX3CR1, ABCA5, TMTC1, CYBRD1, TFF1, SYNM,C2orf40,AMIGO2, AGR2, PTN, CXCL14, ITIH5, LGR6, AGR3, KIAA1683, DACH1, PTHLH, SLC40A1, CD36, DCLK1, TSHZ2, NR3C1, DNALI1, EDN3, EDNRB, MYH11, EGFLAM, SALL2, NRG2, RUNDC3B,GLI3,INHBB,SCGB2A1, HOXA7, DYNLRB2, PDE2A, ATP1A2, ACADSB, IGSF10, CDO1, SEPP1, SDPR, FOXA1, CXCL12,CX3CL1, COL14A1, SCGB2A2, ABAT, CAV1, TNS4, CCL28, JAM2, IRX2, HOXA4, DST, ITM2A, GPRASP1, C1orf226, FMO2, C3orf18, IL33, ME3, SCUBE2, PDZK1, CIRBP, CLDN8, PPP1R3C, STC2, THSD4, MAMDC2, TESC, ADAMTS5, AR, TFF3, SFRP1, SEMA3C, GRAMD3, NDN