Table 2. Association analyses of DIAPH1 SNPs with stroke sub-types in the case-control study.

Stroke subtypes	SNP	Group	WT/HT/MT	OR (95% CI)a
				Additive model	Dominant model	Recessive model
IS	rs3805691		CC/CT/TT
		Case	1429/623/109	0.782(0.700-0.874)	0.712(0.622-0.815)	0.883(0.666-1.171)
		Control	1434/990/166	P=1.300×10-5	P=7.986×10-7	P=0.388
	rs251018		TT/TG/GG
		Case	1533/619/46	1.041(0.916-1.182)	1.066(0.923-1.232)	0.893(0.579-1.378)
		Control	1857/663/70	P=0.539	P=0.386	P=0.609
	rs251019		CC/CT/TT
		Case	1322/681/206	0.813(0.734-0.900)	0.685(0.600-0.782)	1.084(0.862-1.362)
		Control	1277/1082/231	P=6.200×10-5	P=1.899×10-8	P=0.491
	rs7703688		TT/TC/CC
		Case	1638/509/61	1.721(1.486-1.993)	1.771(1.504-2.086)	3.076(1.790-5.287)
		Control	2164/401/25	P=4.139×10-12	P=6.923×10-12	P=4.800×10-5
	rs11954998		TT/TC/CC
		Case	1336/763/60	1.537(1.356-1.743)	1.626(1.410-1.874)	1.752(1.159-2.650)
		Control	1893/644/53	P=2.058×10-11	P=2.275×10-11	P=0.008
HS	rs3805691		CC/CT/TT
		Case	411/296/41	0.979(0.809-1.185)	1.023(0.808-1.295)	0.771(0.449-1.322)
		Control	1434/990/166	P=0.830	P=0.850	P=0.344
	rs251018		TT/TG/GG
		Case	548/176/24	0.941(0.745-1.189)	0.945(0.726-1.231)	0.831(0.372-1.855)
		Control	1857/663/70	P=0.978	P=0.677	P=0.652
	rs251019		CC/CT/TT
		Case	392/284/67	0.972(0.814-1.160)	0.940(0.743-1.188)	1.042(0.691-1.569)
		Control	1277/1082/231	P=0.754	P=0.604	P=0.845
	rs7703688		TT/TC/CC
		Case	610/126/15	1.103(0.832-1.463)	1.078(0.787-1.476)	1.633(0.605-4.411)
		Control	2164/401/25	P=0.494	P=0.640	P=0.333
	rs11954998		TT/TC/CC
		Case	547/181/20	1.101(0.870-1.393)	1.107(0.853-1.438)	1.238(0.549-2.791)
		Control	1893/644/53	P=0.424	P=0.445	P=0.606

IS: ischemic stroke; HS: hemorrhagic stroke. The allele frequencies of all SNPs in controls were consistent with HWE; HWE P-values for rs3805691, rs251018, rs251019, rs7703688, and rs11954998 were 0.780, 0.244, 0.933, 0.184, and 0.837 respectively.

a: Adjusted for age, gender, smoking status, drinking status, TC, TG, LDL-C, HDL-C, T2DM, and hypertension.