. 2020 Jan 3;12(1):416–435. doi: 10.18632/aging.102631

Table 3. Association analyses of DIAPH1 SNPs and hypertension and stroke in the cohort study.

End point	SNP	Genotype	N	Person-years	Incidence density (/10⁴)	HR (95% CI)
End point	SNP	Genotype	N	Person-years	Incidence density (/10⁴)	Additive model	Dominant model	Recessive model
Hypertension	rs3805691	CC	347	5059.10	685.89	1.019 (0.896-1.166)	1.022 (0.874-1.206)	1.031 (0.734-1.447)
		CT	230	3383.53	682.72	P=0.744^a	P=0.748^a	P=0.862^a
		TT	36	551.32	652.98
	rs251018	TT	435	6315.13	690.41	0.964 (0.831-1.118)	0.960 (0.806-1.144)	0.937 (0.605-1.453)
		TG	157	2352.28	667.44	P=0.630^a	P=0.650^a	P=0.772^a
		GG	21	326.53	643.13
	rs251019	CC	306	4311.25	712.09	0.910 (0.808-1.026)	0.872 (0.744-1.022)	0.920 (0.712-1.19)
		CT	241	3724.56	647.06	P=0.123^a	P=0.092^a	P=0.525^a
		TT	66	958.13	688.84
	rs7703688	TT	503	7373.11	683.57	0.877 (0.728-1.056)	0.902 (0.733-1.111)	0.489 (0.218-1.095)
		TC	104	1470.03	707.47	P=0.166^a	P=0.333^a	P=0.082^a
		CC	6	148.27	404.67
	rs11954998	TT	446	6488.01	688.96	0.877 (0.745-1.032)	0.865 (0.723-1.035)	0.837 (0.46-1.524)
		TC	156	2335.90	667.84	P=0.113^a	P=0.113^a	P=0.561^a
		CC	11	170.04	646.91
Stroke	rs3805691	CC	104	11943.44	87.07	1.025 (0.796-1.319)	0.887 (0.663-1.186)	1.166 (0.655-2.075)
		CT	64	7919.26	80.82	P=0.851^b	P=0.419^b	P=0.601^b
		TT	15	1281.25	117.07
	rs251018	TT	133	14859.96	89.50	1.239 (0.943-1.627)	1.178 (0.858-1.615)	2.224 (1.081-4.574)
		TG	44	5689.45	77.34	P=0.124^b	P=0.311^b	P=0.030^b
		GG	6	598.16	100.31
	rs251019	CC	90	10196.63	88.26	1.111 (0.894-1.381)	1.103 (0.829-1.469)	1.264 (0.791-2.018)
		CT	74	8973.51	82.46	P=0.343^b	P=0.501^b	P=0.327^b
		TT	19	1977.42	96.08
	rs7703688	TT	149	17468.61	85.29	1.385 (1.001-1.918)	1.345 (0.936-1.935)	2.882 (1.038-8.004)
		TC	31	3451.09	89.83	P=0.049^b	P=0.109^b	P=0.042^b
		CC	3	222.77	134.67
	rs11954998	TT	129	15450.27	83.49	0.880 (0.661-1.171)	1.004 (0.731-1.379)	0.215 (0.03-1.541)
		TC	53	5283.27	100.32	P=0.631^b	P=0.982^b	P=0.126^b
		CC	1	414.02	24.15

a: Adjusted for age, gender, TC, TG, HDL-C, LDL-C, smoking, drinking, BMI and GLU.

b: Adjusted for age, gender, TC, TG, HDL-C, LDL-C, smoking, drinking, BMI, T2DM and hypertension