Table 1. Correlation of CCL14 mRNA expression and prognosis in hepatocellular carcinoma with different clinicopathological factors by Kaplan-Meier plotter.
Clinicopathological factors | Overall survival | Progression-free survival | |||||
N | Hazard ratio | P-value | N | Hazard ratio | P-value | ||
SEX | |||||||
Female | 118 | 0.59(0.34-1.03) | 0.061 | 120 | 0.7(0.42-1.16) | 0.16 | |
Male | 246 | 0.37(0.23-0.6) | 1.8e-05 | 246 | 0.56(0.39-0.8) | 0.0013 | |
Stage | |||||||
1 | 170 | 0.45(0.24-0.86) | 0.014 | 171 | 0.91(0.55-1.49) | 0.69 | |
2 | 83 | 0.39(0.17-0.9) | 0.023 | 85 | 0.74(0.41-1.33) | 0.31 | |
1+2 | 253 | 0.52(0.32-0.85) | 0.0074 | 256 | 0.64(0.44-0.93) | 0.019 | |
3 | 83 | 0.45(0.25-0.82) | 0.0075 | 85 | 1(0.58-1.72) | 1 | |
4 | 5 | - | - | 5 | - | - | |
3+4 | 87 | 0.5(0.28-0.89) | 0.016 | 90 | 1.03(0.61-1.74) | 0.92 | |
Grade | |||||||
1 | 55 | 0.67(0.26-1.72) | 0.4 | 55 | 0.89(0.4-1.95) | 0.77 | |
2 | 174 | 0.52(0.31-0.87) | 0.012 | 175 | 0.57(0.37-0.88) | 0.01 | |
3 | 118 | 0.39(0.21-0.75) | 0.003 | 119 | 0.74(0.45-1.21) | 0.23 | |
4 | 12 | - | - | 12 | - | - | |
AJCC_T | |||||||
1 | 180 | 0.48(0.26-0.89) | 0.017 | 180 | 0.86(0.53-1.39) | 0.54 | |
2 | 90 | 0.35(0.16-0.76) | 0.0059 | 92 | 0.68(0.4-1.18) | 0.17 | |
3 | 78 | 0.47(0.26-0.86) | 0.012 | 78 | 1(0.57-1.77) | 0.99 | |
4 | 13 | - | - | 13 | - | - | |
Vascular invasion | |||||||
yes | 90 | 0.46(0.21-1.02) | 0.05 | 91 | 0.73(0.42-1.29) | 0.28 | |
None | 203 | 0.46(0.27-0.78) | 0.0033 | 204 | 0.68(0.44-1.06) | 0.088 | |
Race | |||||||
White | 181 | 0.66(0.41-1.04) | 0.071 | 183 | 0.62(0.41-0.92) | 0.016 | |
Asian | 155 | 0.3(0.16-0.58) | 0.00015 | 155 | 0.61(0.38-0.98) | 0.04 | |
Alcohol consumption | |||||||
yes | 115 | 0.52(0.27-1.0) | 0.0048 | 115 | 0.5(0.3-0.85) | 0.0088 | |
none | 202 | 0.53(0.33-0.85) | 0.0068 | 204 | 0.66(0.44-0.99) | 0.042 | |
Virus hepatitis | |||||||
Yes | 150 | 0.68(0.35-1.29) | 0.23 | 152 | 0.65(0.41-1.04) | 0.068 | |
None | 167 | 0.38(0.24-0.62) | 4.1e-05 | 167 | 0.44(0.28-0.69) | 0.00021 |
Bold values indicate P < 0.05.