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Collagen VI mutation and overexpression positively correlated with the progression-free survival of HCC patients. (A–B) Scatter plot comparison of mRNA levels (COL4A1, COL4A2, PXDN, and SPARC) between genomic altered and unaltered groups (A: COL4A1, B: COL4A2). (C) Column plot illustration of activated signaling pathways in COL4A1/COL4A2 genomic altered HCC samples. (D) Kaplan-Meier survival analysis of HCC patients with or without altered COL4A2 DNA sequences.
