Table 1. The expression of lnc-BMP1-1 and clinical characteristics of lung cancer patients.
Clinical characteristics | lnc-BMP1-1 expression N(%) | Total Cases N(%) | Pa | |
Low | High | |||
Age | ||||
<60 | 139 (84.2) | 26 (15.8) | 165 (56.3) | 0.499 |
≥60 | 104 (81.2) | 24 (18.8) | 128 (43.7) | |
Gender | ||||
Male | 177 (85.5) | 30 (14.5) | 207 (70.6) | 0.069 |
Female | 66 (76.7) | 20 (23.3) | 86 (29.4) | |
Smoking | ||||
No | 77 (76.2) | 24 (23.8) | 101 (34.5) | 0.027 |
Yes | 166 (86.5) | 26 (13.5) | 192 (65.5) | |
Drinking | ||||
No | 185 (83.3) | 37 (16.7) | 222 (75.8) | 0.749 |
Yes | 58 (81.7) | 13 (18.3) | 71 (24.2) | |
tumor history | ||||
No | 213 (83.5) | 42 (16.5) | 255 (87.0) | 0.484 |
Yes | 30 (78.9) | 8 (21.1) | 38 (13.0) | |
Lc history | ||||
No | 228 (83.5) | 45 (16.5) | 273 (93.2) | 0.354 |
Yes | 15 (75.0) | 5 (25.0) | 20 (6.8) | |
Clinical Stage | ||||
Ⅰ+Ⅱ | 93 (86.9) | 14 (13.1) | 107 (36.5) | 0.170 |
Ⅲ+Ⅳ | 150 (80.6) | 36 (19.4) | 186 (63.5) | |
Histological subtype | ||||
Adenocarcinoma | 112 (82.4) | 24 (17.6) | 136 (46.4) | 0.189 |
Squamous carcinoma | 70 (79.5) | 18 (20.5) | 88 (30.0) | |
Large cell carcinoma | 8 (72.7) | 3 (27.3) | 11 (3.8) | |
Small cell carcinoma | 27 (96.4) | 1 (3.6) | 28 (9.6) | |
Others | 26 (86.7) | 4 (13.3) | 30 (10.2) | |
T status | ||||
1+2 | 126 (80.3) | 31 (19.7) | 157 (53.6) | 0.190 |
3+4 | 117(86.0) | 19 (14.0) | 136 (46.4) | |
N status | ||||
0 | 91 (79.1) | 24 (20.9) | 115 (39.2) | 0.164 |
1+2+3 | 152 (85.4) | 26 (14.6) | 178 (60.8) | |
M status | ||||
0 | 161 (78.5) | 44 (21.5) | 205 (70.0) | 0.002 |
1 | 82 (93.2) | 6 (6.8) | 88 (30.0) |
NOTE: Comparisons between groups were analyzed as described in the Methods. Groups: High=patients with higher expression of lnc-BMP1-1 in lung cancer tissues compared with their adjacent normal lung tissues; Low = patients with lower expression of lnc-BMP1-1 in lung cancer tissues compared with their adjacent normal lung tissues. a, Pearson χ2 test for high vs. low gene (lnc-BMP1-1 or Cav-I) expression groups combining clinical characteristics. Significance (bold values), p<0.05.
Abbreviations: N, number of subjects in each group; Lc history, lung cancer history.