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. 2020 Jan 4;12(1):462–480. doi: 10.18632/aging.102633

Table 1. The expression of lnc-BMP1-1 and clinical characteristics of lung cancer patients.

Clinical characteristics lnc-BMP1-1 expression N(%) Total Cases N(%) Pa
Low High
Age
 <60 139 (84.2) 26 (15.8) 165 (56.3) 0.499
 ≥60 104 (81.2) 24 (18.8) 128 (43.7)
Gender
 Male 177 (85.5) 30 (14.5) 207 (70.6) 0.069
 Female 66 (76.7) 20 (23.3) 86 (29.4)
Smoking
 No 77 (76.2) 24 (23.8) 101 (34.5) 0.027
 Yes 166 (86.5) 26 (13.5) 192 (65.5)
Drinking
 No 185 (83.3) 37 (16.7) 222 (75.8) 0.749
 Yes 58 (81.7) 13 (18.3) 71 (24.2)
tumor history
 No 213 (83.5) 42 (16.5) 255 (87.0) 0.484
 Yes 30 (78.9) 8 (21.1) 38 (13.0)
Lc history
 No 228 (83.5) 45 (16.5) 273 (93.2) 0.354
 Yes 15 (75.0) 5 (25.0) 20 (6.8)
Clinical Stage
 Ⅰ+Ⅱ 93 (86.9) 14 (13.1) 107 (36.5) 0.170
 Ⅲ+Ⅳ 150 (80.6) 36 (19.4) 186 (63.5)
Histological subtype
 Adenocarcinoma 112 (82.4) 24 (17.6) 136 (46.4) 0.189
 Squamous carcinoma 70 (79.5) 18 (20.5) 88 (30.0)
 Large cell carcinoma 8 (72.7) 3 (27.3) 11 (3.8)
 Small cell carcinoma 27 (96.4) 1 (3.6) 28 (9.6)
 Others 26 (86.7) 4 (13.3) 30 (10.2)
T status
 1+2 126 (80.3) 31 (19.7) 157 (53.6) 0.190
 3+4 117(86.0) 19 (14.0) 136 (46.4)
N status
 0 91 (79.1) 24 (20.9) 115 (39.2) 0.164
 1+2+3 152 (85.4) 26 (14.6) 178 (60.8)
M status
 0 161 (78.5) 44 (21.5) 205 (70.0) 0.002
 1 82 (93.2) 6 (6.8) 88 (30.0)

NOTE: Comparisons between groups were analyzed as described in the Methods. Groups: High=patients with higher expression of lnc-BMP1-1 in lung cancer tissues compared with their adjacent normal lung tissues; Low = patients with lower expression of lnc-BMP1-1 in lung cancer tissues compared with their adjacent normal lung tissues. a, Pearson χ2 test for high vs. low gene (lnc-BMP1-1 or Cav-I) expression groups combining clinical characteristics. Significance (bold values), p<0.05.

Abbreviations: N, number of subjects in each group; Lc history, lung cancer history.