Table 2. The expression of Cav-1 and clinical characteristics of lung cancer patients.
Clinical characteristics | Cav-1 expression N(%) | Total Cases N(%) | Pa | |
Low | High | |||
Age | ||||
<60 | 133(80.6) | 32(19.4) | 165(56.3) | 0.757 |
≥60 | 105(82.0) | 23(18.0) | 128(43.7) | |
Gender | ||||
Male | 171(82.6) | 36(17.4) | 207(70.6) | 0.348 |
Female | 67(77.9) | 19(22.1) | 86(29.4) | |
Smoking | ||||
No | 74(73.3) | 27(26.7) | 101(34.5) | 0.011 |
Yes | 164(85.4) | 28(14.6) | 192(65.5) | |
Drinking | ||||
No | 180(81.1) | 42(18.9) | 222(75.8) | 0.909 |
Yes | 58(81.7) | 13(18.3) | 71(24.2) | |
tumor history | ||||
No | 207(81.1) | 48(18.9) | 255(87.0) | 0.953 |
Yes | 31(81.6) | 7 (18.4) | 38(13.0) | |
Lc history | ||||
No | 222(81.3) | 51(18.7) | 273(93.2) | 0.775 |
Yes | 16(80.0) | 4(20.0) | 20 (6.8) | |
Clinical Stage | ||||
Ⅰ+Ⅱ | 87(81.3) | 20(18.7) | 107(36.5) | 0.979 |
Ⅲ+Ⅳ | 151(81.2) | 35(18.8) | 186(63.5) | |
Histological subtype | ||||
Adenocarcinoma | 113(83.1) | 23(16.9) | 136(46.4) | 0.149 |
Squamous carcinoma | 72(81.8) | 16(18.2) | 88(30.0) | |
Large cell carcinoma | 6(54.5) | 5(45.5) | 11(3.8) | |
Small cell carcinoma | 21(75.0) | 7(25.0) | 28(9.6) | |
Others | 26(86.7) | 4(13.3) | 30(10.2) | |
T status | ||||
1+2 | 128(81.5) | 29(18.5) | 157(53.6) | 0.887 |
3+4 | 110(80.9) | 26(19.1) | 136(46.4) | |
N status | ||||
0 | 93(80.9) | 22(19.1) | 115(39.2) | 0.899 |
1+2+3 | 145(81.5) | 33(18.5) | 178(60.8) | |
M status | ||||
0 | 171(83.4) | 34(16.6) | 205(70.0) | 0.144 |
1 | 67(76.1) | 21(23.9) | 88(30.0) |
NOTE: Comparisons between groups were analyzed as described in the Methods. Groups: High=patients with higher expression of Cav-1 in lung cancer tissues compared with their adjacent normal lung tissues; Low = patients with lower expression of Cav-1 in lung cancer tissues compared with their adjacent normal lung tissues. a, Pearson χ2 test. Significance (bold values), p<0.05.
Abbreviations: N, number of subjects in each group; Lc history, lung cancer history.