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. 2020 Jan 4;12(1):462–480. doi: 10.18632/aging.102633

Table 2. The expression of Cav-1 and clinical characteristics of lung cancer patients.

Clinical characteristics Cav-1 expression N(%) Total Cases N(%) Pa
Low High
Age
 <60 133(80.6) 32(19.4) 165(56.3) 0.757
 ≥60 105(82.0) 23(18.0) 128(43.7)
Gender
 Male 171(82.6) 36(17.4) 207(70.6) 0.348
 Female 67(77.9) 19(22.1) 86(29.4)
Smoking
 No 74(73.3) 27(26.7) 101(34.5) 0.011
 Yes 164(85.4) 28(14.6) 192(65.5)
Drinking
 No 180(81.1) 42(18.9) 222(75.8) 0.909
 Yes 58(81.7) 13(18.3) 71(24.2)
tumor history
 No 207(81.1) 48(18.9) 255(87.0) 0.953
 Yes 31(81.6) 7 (18.4) 38(13.0)
Lc history
 No 222(81.3) 51(18.7) 273(93.2) 0.775
 Yes 16(80.0) 4(20.0) 20 (6.8)
Clinical Stage
 Ⅰ+Ⅱ 87(81.3) 20(18.7) 107(36.5) 0.979
 Ⅲ+Ⅳ 151(81.2) 35(18.8) 186(63.5)
Histological subtype
 Adenocarcinoma 113(83.1) 23(16.9) 136(46.4) 0.149
 Squamous carcinoma 72(81.8) 16(18.2) 88(30.0)
 Large cell carcinoma 6(54.5) 5(45.5) 11(3.8)
 Small cell carcinoma 21(75.0) 7(25.0) 28(9.6)
 Others 26(86.7) 4(13.3) 30(10.2)
T status
 1+2 128(81.5) 29(18.5) 157(53.6) 0.887
 3+4 110(80.9) 26(19.1) 136(46.4)
N status
 0 93(80.9) 22(19.1) 115(39.2) 0.899
 1+2+3 145(81.5) 33(18.5) 178(60.8)
M status
 0 171(83.4) 34(16.6) 205(70.0) 0.144
 1 67(76.1) 21(23.9) 88(30.0)

NOTE: Comparisons between groups were analyzed as described in the Methods. Groups: High=patients with higher expression of Cav-1 in lung cancer tissues compared with their adjacent normal lung tissues; Low = patients with lower expression of Cav-1 in lung cancer tissues compared with their adjacent normal lung tissues. a, Pearson χ2 test. Significance (bold values), p<0.05.

Abbreviations: N, number of subjects in each group; Lc history, lung cancer history.