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. 2020 Jan 23;15(1):e0226681. doi: 10.1371/journal.pone.0226681

Table 5. Cardiovascular risk factors and pregnancy in HHT patients and controls with or without SAA.

  HHT patients P value Control patients  
with SAA without SAA with SAA without SAA P value
n = 42 n = 119 n = 2 n = 75  
Hypertension 9 (21.4%) 18 (15.1%) 0.35 1 (50%) 12 (16%) 0.31
Smokers 15 (35.7%) 43 (36.1%) 0.96 0 (0%) 34 (45.3%) 0.50
Diabetes 4 (9.5%) 5 (4.2%) 0.24 1 (50%) 7 (9.3%) 0.20
Dyslipidemia 7 (16.7%) 11 (9.2%) 0.25 0 (0%) 13 (17.3%) 1
History of CVD 11 (26.2%) 19 (15.9%) 0.12 0 (0%) 27 (36%) 0.54
Previous pregnancy in women 21/28 (75%) 31/54 (57.4%) 0.12 2/2 (100%) 31/41 (41.3%) 1
Pregnancies > 1 19/28 (67.8%) 21/54 (38.9%) 0.01 2/2 (100%) 25/41 (33.3%) 0.52

CV = Cardiovascular

CVD = Cardiovascular Disease

SAA = Splenic Artery Aneurysm

HHT = Hereditary Hemorrhagic Telangiectasia