Table 5. Multiple logistic regression model exploring factors associated with >50% seizures reduction at month 4.
Variables | OR | 95% CI | p-value | |
---|---|---|---|---|
Phenobarbital + ivermectin | 1.177 | 0.707 | 1.960 | 0.530 |
Phenobarbital alone (reference) | ||||
Female | 0.938 | 0.563 | 1.564 | 0.807 |
Male (reference) | ||||
Age | 1.219 | 1.046 | 1.420 | 0.011 |
Weight (in kg) | 0.972 | 0.912 | 1.036 | 0.385 |
Total number of seizures at baseline | 1.080 | 0.984 | 1.185 | 0.104 |
Nodding seizures | 1.250 | 0.437 | 3.572 | 0.678 |
Other form of epilepsy (reference) | ||||
Duration of epilepsy (years) | 0.813 | 0.701 | 0.943 | 0.006 |
Dose of AED at baseline | 1.073 | 1.023 | 1.125 | 0.004 |
Number of days without AED during the 4th month | 0.920 | 0.822 | 1.029 | 0.146 |
Microfilarial density at baseline | 1.001 | 0.994 | 1.008 | 0.783 |
AED: Anti-epileptic drug; OR: Odds Ratio; CI: Confidence Interval