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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Neurobiol Aging. 2019 Aug 21;83:95–104. doi: 10.1016/j.neurobiolaging.2019.08.016

Table 4.

Reserve by Cortical Gray Matter (GM) and Hippocampus (HC) Interaction Effects (standard errors in parentheses). Separate models were used to test each of the four interactions. Main effects show average rate of global cognitive change for reference individuals with average values on other variables in the model. The interaction effects show how reserve variables modify the effects of brain change variables. (+ p<0.05, ++ p <0.01, +++ p<0.001)

Model Reserve Baseline Reserve Change Brain Change Reserve by Brain Change
Reserve Baseline by GM Change 0.005 (0.004) 0.034 (0.004)+++ 0.048 (0.007)+++ −0.021 (0.005)+++
Reserve Change by GM Change −0.001 (0.004) 0.036 (0.004)+++ 0.047 (0.007)+++ −0.015 (0.006)++
Reserve Baseline by HC Change 0.002 (0.004) 0.036 (0.004)+++ 0.019 (0.005)+++ −0.014 (0.005)++
Reserve Change by HC Change −0.001 (0.004) 0.037 (0.004)+++ 0.020 (0.005)+++ −0.013 (0.004)++