Table 3.

Proportion of 73 HIV-infected infants starting antiretroviral therapy (ART) within 14 days of birth who met virologic and immunologic eligibility criteria for the analytic treatment interruption study by age at ART initiation.

Characteristic	Total			Initiated ART <48 h			Initiated ART 2 to 14 days			p-value
	N	% of total (95% CI) N = 73	% of those in follow-up (95% CI) N = 61	N	% of total (95% CI) N = 46	% of those in follow-up (95% CI) N = 35	N	% of total (95% CI) N = 27	% of those in follow-up (95% CI) N = 26
Deaths	3	4.1 (0.9–11.5)		3	6.5 (1.4–17.9)		0	0 (0–12.8)		0.291*
Loss to Follow-up before 48 weeks	9	12.3 (5.8–22.1)		8	17.4 (7.8–31.4)		1	3.7 (0–19.0)		0.141*
Meets virologic criteria
No: VL not <50 copies/mL by 48 weeks	15	20.6		6	13.0		9	33.3
No: VL <50 copies/mL achieved but confirmed rebound >50 copies/mL	14	19.2		11	23.9		3	11.1
Yes: VL achieved and sustained <50 copies/mL	32	43.8 (32.5–55.2)	52.5 (40.0–65.0)	18	39.1 (25.0–53.2)	51.4 (34.9–68.0)	14	51.9 (33.0–70.7)	53.9 (34.7–73.0)	0.335*
Meets immunologic criteria
No	35			19			16
Yes: CD4+ T-cell% sustained >30%	26		42.6 (30.2–55.0)	16		45.7 (29.2–62.2)	10		38.5 (19.8–57.2)	0.610§
Virologic and immunologic criteria
Meets both	16	21.9 (12.4–31.4)	26.2 (15.2–37.3)	9	19.6 (9.4–33.9)	25.7 (12.5–43.3)	7	25.9 (11.1–46.3)	26.9 (11.6–47.8)	1.000§ 0.567*
Meets virologic but not immunologic	16	21.9	26.2	9	19.6	25.7	7	25.9	26.9
Meets immunologic but not virologic	10	13.7	16.4	7	15.2	20.0	3	11.1	11.5
Meets neither	19	26.0	31.2	10	21.7	28.6	9	33.3	34.6

^⁎Fisher Exact test results among all children (N = 73) comparing proportions between two ART initiation groups.

^§Fisher Exact test results among surviving children (N = 61) comparing proportions between two ART initiation groups

Abbreviations: Antiretroviral treatment (ART), Confidence intervals (CI), Viral load (VL).