Table 3.
Rich club organization and cognitive decline.
| Δ Cognitive Index | Δ Memory | Δ Psychomotor speed | Δ Executive function | |
|---|---|---|---|---|
| Δ Global network characteristics | ||||
| Global efficiency |
.116* [.003, 0.229] |
.004 [−0.115, 0.124] |
.146* [.027, 0.266] |
.090 [−0.029, 0.208] |
| Network strength |
.147** [.036, 0.258] |
.042 [−0.076, 0.160] |
.160** [.042, 0.278] |
.108 [−0.009, 0.225] |
| Δ Connection strength | ||||
| Rich club | .024 [−0.087, 0.136] |
−0.022 [−0.140, 0.096] |
.074 [−0.044, 0.194] |
.000 [−0.117, 0.118] |
| Feeder | .059 [−0.053, 0.172] |
−0.005 [−0.123, 0.113] |
.115 [−0.004, 0.234] |
.054 [−0.064, 0.172] |
| Peripheral |
.164** [.054, 0.274] |
.061 [−0.056, 0.178] |
.151* [.034, 0.268] |
.117* [.001, 0.233] |
Longitudinal associations between network measures and cognitive decline. Data are displayed as standardized betas [95% confidence intervals]. Statistical differences were analyzed using linear regression analyses, adjusted for age, sex and education. *p<0.05; **p<0.01; ***p<0.001.